CD4:CD8 count

(redirected from CD4CD8 count)

CD4:CD8 count

ratio of helper-inducer T lymphocytes to cytotoxic-suppressor T lymphocytes in peripheral blood. T-cell subset analysis is performed by flow cytometry of lymphocytes after incubation with fluorescently tagged monoclonal antibodies to the CD4 surface antigen found on helper-inducer T cells and the CD8 surface antigen found on cytotoxic-suppressor T cells. In healthy people, the CD4:CD8 ratio ranges from 1.6-2.2.
Farlex Partner Medical Dictionary © Farlex 2012

CD4:CD8 count

(kownt)
The ratio of the number of helper-inducer T lymphocytes to cytotoxic-suppressor T lymphocytes, as measured by monoclonal antibodies to the CD4 surface antigen found on helper-inducer T cells, and the CD8 surface antigen found on cytotoxic-suppressor T cells. In healthy people, the ratio ranges between 1.6 and 2.2. The CD4:CD8 ratio is used to monitor for signs of organ rejection after transplants, and to assess the degree of immunocompromise in patients with HIV.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012