CD48

CD48

a glycosylphosphatidylinositol-anchored membrane protein present on T cells, B cells, thymocytes, eosinophils, neutrophils, bronchial epithelium, and salivary glands that may play a role in signal transduction on T cells; absent or defective in patients with paroxysmal nocturnal hemoglobinuria.
References in periodicals archive ?
SGN-CD48A is an investigational ADC targeted to the protein CD48, which is highly expressed on MM cells.
En el lavado broncoalveolar hay aumento de los eosinofilos y en la sangre periferica, de la expresion de CD48, el cual puede actuar como molecula de adhesion y atraer eosinofilos a tejidos perifericos como el pulmon, aunque no existe una relacion directa entre la magnitud de expresion y el dano (9).
CD81 and CD48 show different expression on blood eosinophils in systemic sclerosis: new markers for disease and pulmonary inflammation?
In contrast, 23 CD genes (CD3E, CD69, CD48, CD274, CD40L, CD59, CD40, CD93, CD247, CD28, CD5L, CD38, CD44, CD200R1A, CD14, CD5, CD83, CD2, CD200, CD4, CD79B, CD72, and CD180) were significantly increased by 2.
Keywords: WM-68 cell line; anti CD48 antibody; Hybridoma, 0.
CD48 was identified by monClonal antibody using WM-68 and has been shown to possess the bindingaffinity towards B-cell malignancies including chronic lymphCytic leukemia, non-Hodgkins lymphoma and acute leukemia (Henniker et al.
More recently, a study has shown that the HERV-K18 retrovirus, through its CD48 region, participates in the pathogenesis of T1DM.
In addition, CD48 the proposed ligand for CD2, shows at least 47 different glycan structures (18).
In the comparison of B-CLL and myeloid leukemia, most of the statistically significant probes with higher hybridization signals in B-CLL samples represented B lymphocyte-associated genes, such as BTG1, CD79A, FAIM3, CCR7, CD48, and HLA-DRA (28).
In the July 6 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, the researchers identify CD48, which adorns the surface of mast cells, as the protein that performs that binding.
21 de la Organizacion Mundial de la Salud (OMS) (2) y la Perspectiva Regional sobre Salud Publica, Innovacion y Propiedad Intelectual (PR-SPIPI) aprobada en la Resolucion CD48.
Tenders are invited for Anti-Mouse CD48 FITC 100ug with 15 more Items.