CD45 antigen | definition of CD45 antigen by Medical dictionary
CD45 (redirected from CD45 antigen)
a type I transmembrane protein present on all hemopoietic cells (except erythrocytes) that assists in cell activation; expressed in lymphomas, B-cell chronic lymphocytic leukemia, hairy cell leukemia, and acute nonlymphocytic leukemia.
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References in periodicals archive
Although specific signals of CD45 antigen labeled by Alexa Fluor 647 were detectable in the 633-nm channel, coexpression of CD68/PM-2K and CD45 antigens still could not be achieved.
To test the effects of AutoFluo Quencher on IF staining of FFPE bone marrow sections, markers of monocytes (coexpression of CD68/PM-2K and CD45 antigens) were detected by IF staining in AML with reticulin myelofibrosis.
CD45 is a protein antigen expressed on all haemopoietic white cells and "gating" the CD45 antigen
positive cells in each sample was performed as part of the DHR assay in this study.
The CD45 antigen
, expressed on the T cell surface, presents two different isoforms, RA and RO.
Lack of CD45 antigen
on blast cells in childhood acute lymphoblastic leukemia is associated with chromosomal hyperdiploidy and other favorable prognostic features.