CD44 antigen | definition of CD44 antigen by Medical dictionary
CD44 (redirected from CD44 antigen)
a type I transmembrane protein present on T cells, pre-B cells, monocytes, neutrophils, CNS white matter, fibroblasts, skeletal muscle, and medullary thymocytes; facilitates lymphocyte binding to endothelial venules and assists in adhesion.
CD44 A gene on chromosome 11q13 that encodes a cell surface glycoprotein involved in cell–cell interactions, cell adhesion and cell migration, and which is a receptor for hyaluronic acid. CD44 also interacts with other ligands—e.g., osteopontin, collagens and matrix metalloproteinases—and participates in a range of cellular functions including lymphocyte activation, recirculation and homing, haematopoiesis and tumour metastasis.
References in periodicals archive
2006) Expression and glycosylation with polylactosamine of CD44 antigen
on macrophages during follicular atresia in pig.
The cut-off of 22 000 ng/mL represents the mean CD44 antigen
level in the patient cohort.
The best combinations for Cyp1b1 were Ahr, melanoma growth-simulating activity-alpha (Gro1) oncogene, and Cd44 antigen
with CoD of 0.