CD43


Also found in: Wikipedia.

CD43

a type I transmembrane protein present on thymocytes, T cells, granulocytes, monocytes, natural killer cells, platelets, brain, activated B cells, plasma cells, and hemopoietic stem cells that serves as a ligand for CD54 and facilitates cell-cell adhesion; expressed on some myelomas and lymphomas.
References in periodicals archive ?
Adenoid BCC may be confused with adenoid cystic carcinoma, in which setting CD117 and CD43 may be useful.
Pathological biopsy and immunohistochemistry findings (CD20 (+), CD79a (+), CD10 (−), BCL6 (+), MUM (+) CD43 (+), CD5 (+), BCL-2 (+), CD3 (−), PCK (−), EMA (−) KI67 (+), LI: 80% [Figure 1]e and [Figure 1]f) showed diffuse large B-cell lymphoma.
The panel of lymphoid antibodies included: TdT, CD34, CD45, CD19,CD20, CD79, MUM-1 CDI0 ,CD21, CD23, CD3 ,CD4, CD5, CD8, CD15, CD30, CD43, CD56,CD68, MPO, Ki-67, Bcl-2, Bcl-6, Cyclin D1, Kappa, Lamda, ALK-1, ZAP 17 were used.
Granulocytic sarcoma in prostate due to chronic myeloid leukemia in association with benign hyperplasia of prostate is not reported so far, (9) Immunohistochemistry with anti MPO antibodies,CD68, CD43, and CD20,CD33 and CD117 can help in identification of granulocytic sarcoma5 when there is no evidence of peripheral leukemia.
Immunohistochemistry stains were positive for CD20, CD5, CD43, Bcl-2, and cyclin D1.
Introduction of additional markers allowed for further characterization of these subsets indicating that CD14lowCD16+ monocytes expressed higher levels of CD43, CD115, CXCL16, CXCR1 and C3AR1 expression whereas CD14highCD16- monocytes exhibited higher levels of CD1d, CD93 and CD114.
Leukotuximab is an anti-leukemic agent for JL-1+ acute leukemia that targets JL-1 Ag, an epitope of human CD43 extracellular domain.
This structure is composed of concentric rings each containing a peculiar mix of molecules: c-SMAC (central-SMAC) composed of 0 isoform of protein kinase C, CD2, CD4, CD8, CD28, Lck, and Fyn; p-SMAC (peripheral-SMAC) composed of the lymphocyte function-associated antigen-1 (LFA-1), CTLA-4, and the cytoskeletal protein talin; d-SMAC (distal-SMAC) composed of CD43 and CD45 molecules.
The primary antibodies used for immunocytochemistry were as follows: CD2 (clone AB75, NeoMarkers); CD3 (clone SP7, NeoMarkers); CD4 (clone 4B12, DAKO); CD5 (clone CD5/54/F6, DAKO); CD7 (clone 272, NeoMarkers); CD8 (clone C8/144B, DAKO); CD19 (clone LE-CD19, DAKO); CD20 (clone L26, NeoMarkers); CD30 (clone Ber-H2, DAKO); CD43 (clone DF-T1, NeoMarkers); CD45 (Clone 2B11 + PD7/26, DAKO); CD138 (clone M115, DAKO); ALK-1 (clone ALKO1, NeoMarkers); EMA (clone E29, DAKO); EBV/LMP (clone CS.
while they were negative to CD15, CD30, CD45RO, CD43, CD23, CD21, CK116, PLAP, ALK, HMB45, EMA, CD20, CD79a, Cyclin Di, lysosim, actin and desmin.
Immunohistochemically, the cells were positive for CD3 (cytoplasmic stain), CD56 (figure, B), CD43, CD30, TIA-1, and granzyme B.
Venia cada seis meses y me hacian mi examen y tenia 500 o 600 de CD43 y yo le decia al doctor: '?