Several studies on inter-laboratory and inter-method variability of CD4 count
have been published and most show good agreement and interchangeabilite (7,10,11) Two studies, however, found significant variations across different laboratories.
Pearson's correlation coefficient obtained to evaluate the correlation between the coagulation factors and CD4 count
Patients were considered eligible for immediate antiretroviral treatment if they had a CD4 count
at or below 215 cells/m[m.
People with a CD4 count
of 200 or less, as well as pregnant women and people with tuberculosis were getting the treatment from the state facilities previously.
There were no significant differences in ALT values (median, interval between and during high ALT periods), CD4 count
, or HIV viral load of those who exhibited HEV seroconversion compared to those who did not.
Initiations of highly active antiretroviral treatment (HAART) in HIV patients with CD4 count
<200 significantly reduced ocular manifestations viz-a-viz those seen in pre-HAART period.
After adjustment for time since enrollment and CD4 count
, use of antiretrovirals was associated with a 92% reduction in the incidence of transmission (incidence rate ratio, 0.
The analysis demonstrated a clear difference in CD4 count
between two trial groups after 52 weeks.
The diagnosis of PTB/HIV co-infection was based on criteria for diagnosing TB in poor resource settings where there are no facilities and manpower for mycobacterium tuberculosis culture: (a) the diagnostic criteria of TB given in the World Health Organisation (WHO) treatment of tuberculosis guideline for national programmes ; (b) specificity of clinical criteria in diagnosing TB patient [6, 10]; (c) Although Mantoux is usually negative in HIV infection because of loss of cell mediated immunity due to depletion of CD4 count
, HIV patients who were smear negative for AAFB, but had positive Mantoux test with an area of induration [greater than or equal to]10mm diameter were considered diagnostic for tuberculosis.
Interpretation & conclusions: Parasitic infections were detected in 35 per cent HIV infected patients and low CD4 count
was significantly associated with opportunistic infection.
We present an unusual case of CMV retinitis occurring less than 6 weeks after commencing HAART, in a patient with no signs of CMV disease at baseline ophthalmology assessment, and with a CD4 count
of 280 cells/[mm.
Blood selenium levels, CD4 count
(a measure of immune function), and HIV viral load (the number of copies of the virus in the blood) were assessed at the study's beginning and end.