jiroveci pneumonia with no improvement (Table 1 and figure 2: A and B) and patient number 2 had TB but the TB therapy was given only after his CD4+ lymphocytes
had risen in response to anti-herpes virus treatment (Table 1 and figure 2: A and B).
Cells having three or more latex particles attached to them (rosettes) were counted as CD4+ lymphocytes
The levels of T CD4+ lymphocytes
and viral load were obtained from data of the reports on the patients' charts.
Absolute count and percentage of CD4+ lymphocytes
are independent predictors of disease progression in HIV-infected persons initiating highly active antiretroviral therapy.
Initial increase in blood CD4+ lymphocytes
after HIV antiretroviral therapy reflects redistribution from lymphoid tissues.
HIV infection undermines cell-mediated immunity through depletion of CD4+ lymphocytes
which leads to reactivation of TB in HIV-infected people and increases susceptibility to new infections [1-4].
A subtle shift from the response of Th1 (cellular immunity) CD4+ lymphocytes
to a proportional increase in the Th2 (humoral, progesterone, estrogen, corticosteroids, [alpha]-fetoprotein, prolactin, and [alpha]-globulin) may also contribute to decreased resistance.
The CD4+ lymphocytes
are primed to recognize previous antigenic stimuli and thus may be responsible for manifestations of IRIS seen soon after HARRT (4).