platelet glycoprotein IV deficiency(redirected from CD36 deficiency)
platelet glycoprotein IV deficiencyAn inherited haematologic disorder (OMIM:608404) characterised by a complete type I (complete CD36 deficiency) phenotype, in which platelets and monocytes/macrophages have no CD36, and type II (partial CD36 deficiency) phenotype, in which there is no surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal.
Defects in CD36, which encodes the fourth major platelet surface glycoprotein (PGIV), a receptor for thrombospondin, cause platelet glycoprotein deficiency.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.