CD35

CD35

a type I transmembrane protein present on monocytes, granulocytes, dendritic cells, red blood cells, some T cells, and glomerular podocytes that facilitates phagocytosis and/or binding of immune complexes; expressed in Wilms tumor.
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Immunohistochemically, FDCS show strong positivity for CD21, CD23 and CD35 and occasional positivity for S-100, CD68, leukocyte common antigen and muscle specific actin.
Immunohistochemical analysis showed that the spindle cells in the submucosal were positive for CD34 [Figure 3]a and negative for CD117, platelet-derived growth factor receptor-alpha (PDGFRA) [Figure 3]b, DOG-1, S-100 protein, desmin, smooth muscle actin, fascin, and CD35.
52) CD21 and another dendritic cell antigen, CD35, but not CD23, can aid in the diagnosis of MALT lymphoma in 2 ways.
low/-] B lymphocytes have been found enriched in patients with autoimmune diseases [26, 27] and these cells also fail to express CD35 (our unpublished results).
Immunohhistochemical Marker Cell type CD45 CD21 CD23 CD35 SI00 CDla Langerin Fascin LCH LC (+) (-) (-) (-) (+) (+) (+) only + IDC (+) (-) (-) (-) (+) (-) (-) (+) Macrophage or (+) (-) (-) (-) (+/-) (-) (-) (+/-) histiocyte l/DDC (+) (-) (-) (-) (-/+) (-) (-) (+) pDC (-) (-) (-) (-) (-) (-) (-) (-) FDC (-) (+) (+) (+) (+/-) (-) (-) (+) FRC (+) (-) (-) (-) (-) (-) (-) Cell type Clusterin CD68 CD123 CD163 CD4 FXIIIa TCLI LC (-) (+) (-) (-) (+) (-) (-) IDC (-/+) (+/-) (-) (-) (+) (-) y Macrophage or (-) (+) (-) (+) (+) (-) (-) histiocyte l/DDC (-) (+) (-) (-) (+/-) (+) (-) pDC (-) (+) (+.
In an effort to understand the pathogenesis of anaemia in Pf infection we studied the relationship between expression level of CD35, CD55 and CD59 with haemoglobin status in a group of malaria cases from three regions of India, namely Assam, Goa and Chennai.
En conjunto estas celulas muestran expresion intensa de HLA-DR con positividad variable para marcadores mielomonociticos, moleculas de adhesion (CD11a, CD18), receptores para complemento (CD21, CD35, CD23 y receptores de quemoquinas (CXCR4, CXCR3) entre otros (18;19).
Immunohistochemical stains were positive for CD21, CD23, and CD35 and negative for CDlp, S-100, CD20, CD3, CD31, CD34, and cytokeratin.
But FDCS is positive for one or more of the follicular dendritic cell markers such as CD21, CD35, CD23, KiM4p and CNA.
In immunohistochemical study, these cells were positive for CD163, lysozyme, CD4, and CD43, while CD117, MPO, CD68, langerin, CD1a, S-100, CD35, CD21, clusterin, fascin, factor 13a, CD123, TCL-1, TdT, CD3, CD20, and CD30 were all negative.
4,5,8,15) In most studies CD35 appears to be the most sensitive and reliable marker for this tumor.