CD30l

CD30l

a type III transmembrane protein present on activated T cells and monocytes that can induce differential responses in CD30-expressing cells ranging from growth to cell death.
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A B C D 1 POS POS NEG NEG 2 POS POS NEG NEG 3 GM-CSF IFN [gamma] IL-1 [alpha] IL-1 [beta] 4 GM-CSF IFN [gamma] IL-1 [alpha] IL-1 [beta] 5 IL-13 IL-17 I-TAC KC 6 IL-13 IL-17 I-TAC KC 7 rantes SDF-1 TCA-3 teck 8 rantes SDF-1 TCA-3 teck E F G H 1 Blank BLC CD30L Eotaxin 2 Blank BLC CD30L Eotaxin 3 IL-2 IL-3 IL-4 IL-6 4 IL-2 IL-3 IL-4 IL-6 5 Leptin LIX Lymphotactin MCP-1 6 Leptin LIX Lymphotactin MCP-1 7 TIMP-1 TIMP-2 TNF [alpha] sTNF ri 8 TIMP-1 TIMP-2 TNF [alpha] sTNF RI I j K L 1 Eotaxin-2 Fas Ligand Fractalkine GCSF 2 Eotaxin-2 Fas Ligand Fractalkine GCSF 3 IL-9 IL-10 IL-12p40p70 IL-12p70 4 IL-9 IL-10 IL-12p40p70 IL-12p70 5 MCSF MIG MIP-1 [alpha] MIP-1y 6 MCSF MIG MIP-1 [alpha] MIP-1y 7 sTNF R II Blank Blank POS 8 sTNF R II Blank Blank POS
Besides TNF-alpha and TNF-beta, TNFL superfamily include CD40L, CD30L, FasL, TNF-related apoptosis-inducing ligand (TRAIL), lymphotoxin-beta (LT-beta), LIGHT, receptor activator of NF-kappaB ligand (RANKL), 4-1BBL, CD27L, OX40L, TNF-related weak inducer of apoptosis (TWEAK), a proliferation-inducing ligand (APRIL), B-cell activating factor (BAFF), vascular endothelial cell-growth inhibitor (VEGI), ectodysplasin A (EDA)-A1, EDA-A2, and GITRL [4, 10].