CD24


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CD24

a glycosylphosphatidylinositol-anchored protein present on B cells, pre-B cells, neutrophils, and a few thymocytes that may play a role in inducing B-cell proliferation and differentiation; expressed in patients with B-cell lymphomas and some with B-cell chronic lymphocytic leukemias.
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5 TdT TdT CD14 CD24 CD7 CD15 CD1a CD64 Abbreviations: cy, cytoplasmic; IgM, immunoglobulin M; MPO, myeloperoxidase; sm, surface membrane;TCR, T-cell receptor;TdT, terminal deoxynucleotidyl transferase.
sup][68] Hypoxia induces CD24 (a marker for tumor formation and metastasis) through HIF-1a binding to the promoter in many cancers.
Previous reports suggested the existence of tumor stem cells that are characterized by upregulation of CD44 and the downregulation of CD24 (34).
Objective: Correlation of CD24 expression with histological grading and TNM staging of retinoblastoma.
NDRG2 expression regulates CD24 and metastatic potential of breast cancer cells.
The researchers established that these specific molecules--called CD24 and CD44--were indeed the same between the two species.
The researchers established that these specific molecules - called CD24 and CD44 -- were indeed the same between the two species.
Cell adhesion molecules P-cadherin and CD24 are markers for carcinoma and dysplasia in the biliary tract.
In breast cancer, stem cells that are positive for CD44 and negative or low for CD24 are the most prolific: studies have shown that as few as 100 stem cells with this pattern of markers are sufficient to regenerate tumors.
41] The second factor is our observation that increased CD24 expression independently predicts poor patient survival;[sup.
They concluded that CD133 and CD15 can be used as selectable markers, but CD24 coexpression helps to distinguish foetal mouse multipotent stem cells from neuronal progenitors and postmitotic neurons (21).