CD24


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CD24

a glycosylphosphatidylinositol-anchored protein present on B cells, pre-B cells, neutrophils, and a few thymocytes that may play a role in inducing B-cell proliferation and differentiation; expressed in patients with B-cell lymphomas and some with B-cell chronic lymphocytic leukemias.
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Xiaowen,L., H.Yu, H.Cai and Y.Wang(2014).Expression of Cd24, P21, P53, and C-Myc in Alpha-Fetoprotein-Producing Gastric Cancer: Correlation with Clinicopathologic Characteristics and Survival.
Researchers at the Stanford University School of Medicine have now discovered a new protein, called CD24, that acts as a potent "don't eat me" signal "capable of directly protecting cancer cells from attack".
The leukemic blasts isolated from the BM and spleen of vav-CALM/AF10 TM co-expressed Mac-1, B220, and CD24 with variable expression of CD117 in the absence of other B-cell markers, thus resembling human MPAL with involvement of B and myeloid lineages.
La separacion de celulas que tienen el fenotipo CD44alta/CD24baja, se realizo utilizando el separador MACS Separator Starting kit (Miltenyi), aplicando el protocolo de separacion inmunomagnetica recomendado por el fabricante del kit, que emplea perlas magneticas marcadas con monoclonales CD44 y CD24 y columnas MS (Miltenyi).
Multivariate analysis of oestrogen receptor alpha, pS2, metallothionein and CD24 expression in invasive breast cancers.
The expression and clinical significance of EPCAM, CD44 and CD24 in gastric cancer.
Disease-specific biomarkers such as miR-200c, miR-214, CA-125, Muc-1, and CD24 are contained in exosomes and may alter gene expression in cells [1,7].
In particular, HMGB1, once accumulated in the extracellular milieu, is able to convey danger signals by triggering inflammatory patterns with extracellular signal-regulated kinases (ERKs), p38, and NF-kB activation via several cell surface receptors, including TLR2, TLR4, CD24, and, mainly, RAGE [12, 16, 36].
A number of cell surface markers such as CD44, CD24, and CD133 are often used to identify and enrich CSCs.
Abdul Aziz et al., "CD24, CD44 and EpCAM enrich for tumour-initiating cells in a newly established patient-derived xenograft of nasopharyngeal carcinoma," Scientific Reports, vol.
Another glycoprotein also located in cell surface, CD24, participates in tumor growth and metastasis [116].