CCR6

(redirected from CD196)

CCR6

A gene on chromosome 6q27 that encodes a member of the beta chemokine receptor family, which is similar to G protein-coupled receptors. CCR6 is preferentially expressed by immature dendritic cells and memory T cells, and may be important for B-lineage maturation and antigen-driven B-cell differentiation; it may regulate migration and recruitment of dentritic and T cells during inflammation. Its ligand is macrophage inflammatory protein 3 alpha (MIP-3 alpha).
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References in periodicals archive ?
Antibody mix 1: CD3 PerCP Cy5.5 (BD552852), CD4 V450 (BD560345), CD8 V500 (BD560774), CD197 Alexa Flour 647 (BD557734), CD45RA PE Cy7 (BD560675), CD183 Alexa 488 (BioLegend 353710), and CD196 PE (BioLegend 353410)
difficile reference strain 630 were compared to two hypervirulent strains (CD196 and CDR20291), and five secreted proteins were identified exclusively in the supernatants of the hyper-virulent strains [13].
difficile PCR-ribotype 027 strains (CD196, a nonepidemic strain isolated in France in 1985, and R20291, isolated from an outbreak in Stoke Mandeville, UK, in 2006) have been recently deposited in GenBank (accession nos.
difficile strain CD196 (99) and has been named binary toxin CDT.