CXCR3

(redirected from CD183)

CXCR3

A gene on chromosome 2q21 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor family, which selectively binds CXCL9, CXCL10 and CXCL11; it induces cellular responses involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration.
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Antibody mix 1: CD3 PerCP Cy5.5 (BD552852), CD4 V450 (BD560345), CD8 V500 (BD560774), CD197 Alexa Flour 647 (BD557734), CD45RA PE Cy7 (BD560675), CD183 Alexa 488 (BioLegend 353710), and CD196 PE (BioLegend 353410)
Caption: Figure 2: Percentages of total number of [CD4.sup.+] T cells that are characterized as (a) Th17 cells (CD183 [CD196.sup.+]), (b) Th1 cells ([CD183.sup.+][CD196.sup.-]), and (c) Th2 cells ([CD183.sup.-][CD196.sup.-]).
Naive [CD8.sup.+] T cells CD11a Low CD11c Low CD25 Low CD27 High CD43 Low CD43I Low CD44 Low CD49d Low CD69 Low CD62L High CD70 Low CD95 Low CD95L Low CD122 Low CD127 High CD183 Low CCR5 Low CCR9 Low KLRG-1 Low PD1 Low CTLA-4 Low BTLA Int.