CD15


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CD15

a phosphatidylinositol-anchored transmembrane protein found on neutrophils; it may be involved in phagocytosis; expressed in patients with Hodgkin disease, some B-cell chronic lymphocytic leukemias, acute lymphoblastic leukemias, and most acute nonlymphocytic leukemias.

CD15

This is a retired HUGO symbol for what molecular biologists now term FUT4 (see there). In practice, CD15 is widely used by haematologists, immunologists, laboratorians, pathologists and many others.
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According to the WHO classification (2), Hodgkin and Reed-Sternberg cells are almost always positive for CD30 and positive for CD15 in 75-85% of cases.
13] None of our cases stained for CEA or CD15 (LeuM1), and it has been recommended that these antibodies be used for separating mesothelioma from adenocarcinoma and other epithelial neoplasms, as CD15 and CEA generally lack reactivity with mesothelioma cells.
Los resultados inmunohistoquimicos ganglionares de un panel de anticuerpos contra celulas RS y sus variantes fue reportado como CD15 (+) y CD30 (+++), confirmatorios de LH (1,6).
Sonuc: Laboratuarimizda epiteloid malign mezotelyoma acisindan kalretinin, CK5/6, adenokarsinom acisindan CEA ve CD15 ve bunlara eklenen EMA ve TTF-1'den olusan bir panelin hemen tum olgularda sorunu cozdugunu gorduk.
Por otra parte en la tabla 8 se presentan los niveles de expresion de CD45, CD15, CD33 y CD16 en las celulas dendriticas derivadas del monocito.
99m]Tc-fanolesomab (NeutroSpec[R], Palatin Technologies, Cranbury, NJ), which binds the CD15 antigen expressed on neutrophils.
In a previous study (7) the authors have found the absence of CD15 as a bad predictor for poor overall survival (OS), unlike others who have failed to establish such prognostic value.
A panel of CD30, CD15, PAX5, CD20 and CD3 Immunostains along with in situ hybridisation (ISH) for EBV-encoded RNA (EBER) would usually suffice.
El tumor mieloide extramedular marca positivamente con mieloperoxidasa en el 88% de los casos, con CD15 en el 65%, con CD34 en el 38% y con CD45 en el 20%.
Immunohistochemical stains showed that the large atypical cells were positive for CD15 and CD30, mostly negative for CD20 and Oct 2, and negative for CD79a, CD45, Bob.
Por otra parte, los neutrofilos tambien se benefician de esta interaccion, porque mantienen la expresion de CD13, CD15, CD16 y Mac-1, que son receptores de senales antiapoptoticas por medio de las cuales prolongaran su vida media.