CDH5

(redirected from CD144)

CDH5

A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells. CDH5 is thought to play a key role in endothelial cell biology by controlling cohesion and organisation of intercellular junctions.
References in periodicals archive ?
Then, the cells were incubated with FITC-conjugated anti-CD44 and CD144, phycoerythrin-conjugated anti-CD34 and CD106, and PerCP-conjugated anti-CD105 antibodies (all from Abcam, Cambridge, UK) for 30 min.
After blocking with 5% bovine serum albumin, cells were incubated overnight at 4[degrees]C with specific primary antibody, which was one of CD31 (PECAM-1), CD54 (ICAM-1), CD106 (VCAM-1) and CD144 (VE-cadherin).
We incubated 10 [micro]L EMP suspension with 10 [micro]L antihuman/rat E-selectin, CD144, CD31, and CD42 or isotype control.
Tumor cells stain for the usual vascular and endothelial markers including CD31, CD34, CD144 (VE-cadherin), and at least focally for factor VIII-related antigen.