CD107b

CD107b

a type I transmembrane protein present on activated platelets; increased expression noted on transformation of cells with metastatic potential and on embryonic cells.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
As a consequence, intracellular granules fuse with the cell membrane and preformed mediators [63, 64] are released, and granule membrane molecules like CD11b, CD13, CD63, CD107a, CD107b, CD203c, CD200R, CD300a, and the vascular endothelial growth factor A (VEGF-A) [65-67] are translocated to the outer cell surface, the so-called anaphylactic degranulation.
Lysosomal-associated membrane proteins 1 and 2 (LAMP-1, CD107a; LAMP-2, CD107b)LAMP-1 and 2 integral membrane glycoproteins are found in the lysosomes and dense granules of platelets and serve as markers of platelet activation.
Lysosome-associated membrane proteins h-LAMP1 (CD107a) and h-LAMP2 (CD107b) are activation-depen dent cell surface glycoproteins in human peripheral blood mononuclear cells which mediate cell adhesion to vascular endothelium.