CD104

CD104

a type I transmembrane protein present on epithelia and thymocytes that facilitates adhesion of cells to the extracellular matrix; expressed in squamous cell carcinoma.

ITGB4

A gene on chromosome 17q25 that encodes an integrin beta chain protein (integrins are noncovalently associated transmembrane glycoprotein receptors, composed of alpha and beta chains). The beta chain encoded by ITGB4 usually associates with alpha 6, serving as a laminin receptor. It plays a key structural role in the hemidesmosomes, regulates keratinocyte polarity and motility and is a central player in the biology of invasive cancer.

Molecular pathology
ITGB4 mutations are associated with epidermolysis bullosa with pyloric atresia.
References in periodicals archive ?
When we evaluated the mesenchymal features of the testis-derived colonies, we found that not only did the cells express all the classical markers of MSCs (CD90, CD73, and CD104) but also they differentiated into cells of mesodermal origin with ease.
The following wheat cultivars were evaluated: CD104, CD108, CD116, CD150, CD154, CD1440, CD1550, BRS Guamirim, BRS Pardela, Mirante and Quartzo, intended for grain production.
Os seis tratamentos foram constituidos da seguinte forma: [T.sub.1] ('OR Mirante' x carboxin+thiram); [T.sub.2] ('OR Mirante' x difenoconazole); [T.sub.3] ('OR Mirante' x sem fungicida); [T.sub.4] ('CD 104' x carboxin + thiram); [T.sub.5] ('CD 104' x difenoconazole) e [T.sub.6] ('CD104' x sem fungicida).