CD104

CD104

a type I transmembrane protein present on epithelia and thymocytes that facilitates adhesion of cells to the extracellular matrix; expressed in squamous cell carcinoma.

ITGB4

A gene on chromosome 17q25 that encodes an integrin beta chain protein (integrins are noncovalently associated transmembrane glycoprotein receptors, composed of alpha and beta chains). The beta chain encoded by ITGB4 usually associates with alpha 6, serving as a laminin receptor. It plays a key structural role in the hemidesmosomes, regulates keratinocyte polarity and motility and is a central player in the biology of invasive cancer.

Molecular pathology
ITGB4 mutations are associated with epidermolysis bullosa with pyloric atresia.
References in periodicals archive ?
The following wheat cultivars were evaluated: CD104, CD108, CD116, CD150, CD154, CD1440, CD1550, BRS Guamirim, BRS Pardela, Mirante and Quartzo, intended for grain production.
Local sponsors are CIGNA HealthCare, The Children's Hospital, KDVR Fox 31, the Denver Business Journal and radio stations KYGO, Smooth Jazz CD104.
Local Star Chefs sponsors include Flatirons Land Rover, Southern Wine & Spirits and Smooth Jazz CD104.