pECs MIC2, E2 Adhesion PECAM-1 pECs PECAM-1 molecules Protein Name Ligand CD Ligand Cross-species family name location interaction [alpha]4 CD 106 pECs ECM Yes Yes CD 106 pEC EC (pEC?) Yes U [alpha]6 -- ECM No Integrins [alpha]h, LFA-1 CD54 pECs pECs Yes U CD102
[alpha]M, Mac-1 CD50 pECs ST Yes U [beta]1 [beta]2 VLA-4 fIntegrin VLA-6 dimers LPAM-1 CD 162 pECs No E-selectin CD15s NK U CD43 NK U CD34 Selectins L-selectin -- pEC Yes -- pECs P-selectin CD 162 NK NK No U CD15s pMIC2?
Family Molecule Cellular distribution P-selectin (CD62P) Endothelium activated by histamine or thrombin Selectin E-selectin (CD62E) Endothelium activated by cytokines (TNF-[alpha], IL-10) L-selectin (CD62L) Neutrophils, monocytes, and T and B cells in constitutive form Endothelium activated by ICAM-1 (CD54) cytokines (TNF-[alpha], IL-1[beta]), macrophages, and lymphocytes Immunoglobulin ICAM-2 (CD102
) Endothelium in a constitutive form VCAM-1 Endothelium activated by cytokines (TNF-[alpha], IL-1[beta]) Chemokine CX3CR1 T cells, monocytes, and NK cells in a constitutive form Family Molecule Ligand cell type P-selectin (CD62P) Sialyl Lewis X in PSGL-1 (P-selectin glycoprotein ligand-1) present in neutrophils, monocytes, and T cells (effector and memory) .
Profiling of cell adhesion molecules was also evaluated for CD29, CD44, CD49e, CD54, CD58, CD62, CD102
, CD106, CD146, and CD166 markers.
) is also known as intercellular adhesion molecule 2 (ICAM-2).
(10,20) Mucosa-associated lymphoid tissue lymphomas differ from follicular lymphomas in that they are CD102
and do not exhibit bcl-2 rearrangements.
A gas analysis system consisting of an oxygen gas analyser (Servomex Basic O2 Analyser, 500A, Susses, England) and a carbon dioxide gas analyser (Datax Normocap CO2 moniotr, CD102
, Helsink, Finland) was used to measure samples of expired air.