CCR-2 | definition of CCR-2 by Medical dictionary
CCR2 (redirected from CCR-2)
CCR2 A gene on chromosome 3p21.31 that encodes a receptor for monocyte chemoattractant protein-1 (MCP-1), a chemokine that mediates monocyte chemotaxis through agonist-dependent calcium mobilisation and inhibition of adenylyl cyclase. MCP-1 plays a role in monocyte infiltration in inflammatory responses to rheumatoid arthritis and tumours.
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References in periodicals archive
However, certain persons with mutated CCR-5 can become HIV-infected (10); in such cases other chemokine receptors (e.g., CXCR-4, CCR-2
, and CCR-3) are believed to facilitate infection.
The Mild Brain Injury Program (CCR-2
) is an outpatient day treatment program designed to serve up to eight individuals during a six-to-ten-month period.