RYR1

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RYR1

A gene on chromosome 19q13.1 that encodes a ryanodine receptor found in skeletal muscle, which acts as a calcium channel connecting the sarcoplasmic reticulum and transverse tubules.

Molecular pathology
RYR1 mutations are linked to malignant hyperthermia susceptibility, central core disease and minicore myopathy with external ophthalmoplegia.
References in periodicals archive ?
Greenlick said he ultimately expects all 16 CCOs to oppose the amended bill.
However, because current CCOs "rarely have significant experience in these areas," Russell Reynolds is noticing that firms are "hiring to address these capability gaps.
By undertaking the simple but important steps listed above, senior management can foster a much better working relationship with its CCO and between its CCO and employees.
The CCO needs to have independence and authority to stand alone, performing responsibilities independent from the business and, increasingly, independent from legal.
The training consists of CJTF-HOA mission, CCO overview, Camp Lemonier welcome brief, pertinent campaign plan briefs, country specific briefs and local policies and procedures.
The board said it's gathering information to draft recommendations on CCOs to Gov.
Compliance manuals created by outsourced CCOs were not tailored to registrants' businesses and practices and, thus, the compliance manuals that had been adopted contained policies and procedures that were not appropriate or applicable to the registrants' businesses or practices;
Every business has a unique risk profile--to the company and its industry; every CCO inherits some risk because risk is endemic to business.
Perhaps the need for integrity in a CCO is best understood by considering the opposite of integrity: hypocrisy.
The two key threshold documents (risk assessment and annual CCO review) should be completed on an annual basis.
The CJTF-HOA CCO also has the unique distinction of being the only "contingency contracting" office operated by the Navy.