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Related to CCNU: BCNU, lomustine, CCSU


a nitrosourea alkylating agent used as an antineoplastic agent in treatment of Hodgkin's disease and brain tumors, administered orally. Called also CCNU.


An antineoplastic agent.
Synonym(s): CCNU




A "salvage" chemotherapy regimen used for patients who have a disease—e.g., lymphoma—relapse after radiation therapy or chemotherapy.


Cyclonexyl-chloroethyl-nitrosourea, lomustine Oncology A chemotherapeutic used in adjuvant therapy of high-grade astrocytomas, also used in NHL, melanoma, myeloma, GI CAs Adverse effects N&V, ↓ platelets, ↓ WBCs, 2º leukemia, pulmonary fibrosis, renal failure. See BCNU, Nitrogen mustards.


References in periodicals archive ?
html[greater than] ("No epidemiological study of CCNU as a single agent was available to the Working Group .
Disgraced orthopaedic specialist Paul Vickers, who was jailed for life in 1981 for murdering his wife with the anti-cancer drug CCNU, has applied for parole.
Lomustine Pronunciation: Loe-MUS-teen Commonly referred to as: CCNU Brand names: A commonly used brand name is CeeNU[R].