CCNF


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CCNF

A gene on chromosome 16p13.3 that encodes a member of the cyclin family which regulates cell cycle transitions by binding and activating cyclin-dependent protein kinases. CCNF also belongs to the F-box protein family that constitutes a subunit of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination.
References in periodicals archive ?
In this article, we describe an interesting case of CCNF with thoracic extension.
1) In most of the case series on CCNF, the primary etiology has been an odontogenic infection, although infections secondary to surgery (6) and peritonsillar abscess (11) have also been reported.
Mediastinal extension of CCNF is a very serious complication that can lead to mediastinitis, pericarditis, pleural or pericardial effusion, empyema, pneumonitis, cardiac tamponade, and esophageal bleeding.
Edwards et al recommend that wound dressings and packing be changed in patients with CCNF how often?