CCAAT box | definition of CCAAT box by Medical dictionary
CAAT box (redirected from CCAAT box)
a sequence of nucleotides found in a conserved region of DNA located "upstream" (5' direction) of the start points of eukaryotic transcription units; specific transcription factors appear to associate with it; found in many promoters at -75 bp with the consensus sequence GG(T/C)CAATCT. It is believed to determine the efficiency of transcription.
CAAT box A semi-conserved “box” of DNA with the “consensus” sequence GGCCAATCT, located 75–80 nucleotides upstream—i.e., in the 5’ direction from the start site for transcription of alpha and beta globin genes—forming part of the promoter site for RNA polymerase II.
References in periodicals archive
CONSTANS and the CCAAT box
binding complex share a functionally important domain and interact to regulate flowering of Arabidopsis.