CEBPE

(redirected from CCAAT/enhancer-binding protein epsilon)

CEBPE

A gene on chromosome 14q11.2 that encodes a transcription factor which binds as a homodimer to various DNA regulatory regions, and as a heterodimer to CEBP-delta. CEBP-epsilon is thought to be critical for the terminal differentiation and functional maturation of committed granulocyte progenitors.

Molecular pathology
CEPBE mutations are linked to specific granule deficiency.