CCR3

(redirected from CC chemokine receptor)

CCR3

A gene on chromosome 3p21.3 that encodes a G protein-coupled receptor for C-C-type chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13) and RANTES (CCL5). It is highly expressed in eosinophils and basophils, as well as in TH1 cells, TH2 cells and airway epithelial cells; it may contribute to the accumulation and activation of eosinophils and other inflammatory cells in airways allergies, and is also an entry co-receptor for HIV-1.
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Frequency of the HIV-protective CC chemokine receptor 5-Delta32/Delta32 genotype is increased in hepatitis C.
A Study on the Association between CCR[DELTA]32 Mutation and HCV Infection in Iranian Patients
Mogamulizumab is a humanized monoclonal antibody directed against CC chemokine receptor 4 (CCR4).
FDA approves biologic for mycosis fungoides, Sezary syndrome
Poteligeo is a monoclonal antibody that binds to a protein (called CC chemokine receptor type 4 or CCR4) found on some cancer cells.
United States : FDA approves treatment for two rare types of non-Hodgkin lymphoma
According to the company, Poteligeo is a monoclonal antibody that binds to a protein (called CC chemokine receptor type 4 or CCR4) found on some cancer cells.
The US FDA approves Poteligeo injection for two rare types of non-Hodgkin lymphoma
[18] Other studies also found that receptors of MCP-1, CC chemokine receptor type 1 (CCR1) and CC chemokine receptor type 2 (CCR2), were expressed on the ventral midbrain of humans.
Pretreatment Serum MCP-1 Level Predicts Response to Risperidone in Schizophrenia
We have reported that stimulation by fibronectin increases the release of CCL2 from activated microglia, and CCL2 stimulates the CC chemokine receptor CCR2 of microglia resulting in the stimulation of P2X4R trafficking to the cell surface from lysosomes of microglia (38) (Fig.
Purinergic signaling in microglia in the pathogenesis of neuropathic pain
Chang et al., "Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1," The Journal of Experimental Medicine, vol.
Cannabinoid Receptor 2 Modulates Neutrophil Recruitment in a Murine Model of Endotoxemia
These cytokines stimulate the generation of eotaxin, which acting on CC chemokine receptor 3 (CCR3) on eosinophilsthen stimulate the migration of eosinphils into the lung tissue.
Serum IL-17 and eotaxin levels in asthmatic patients with allergic rhinitis
Petrek, "CC chemokine receptor (CCR)2 polymorphism in Czech patients with myocardial infarction," Immunology Letters, vol.
CCL2 serum levels and adiposity are associated with the polymorphic phenotypes -2518A on CCL2 and 64ILE on CCR2 in a Mexican population with insulin resistance
CC chemokine receptor 5 polymorphism in Italian patients with giant cell arteritis.
Frequency of CCR5[DELTA]32 allele in healthy Bosniak population
The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-Cell leukemia/ lymphoma.
Genetic polymorphisms of CCL22 and CCR4 in patients with lung cancer
The CC chemokine receptor 5 (CCR5) belongs to the trimeric guanine nucleotide-binding-protein-coupled seventransmembrane receptor superfamily, which comprises the largest superfamily of proteins in the body [8]; exerts its activity via G protein; and binds to the chemokines RANTES (CCL5), MIP-1[alpha] (CCL3), and MIP-1[beta] (CCL4) [9].
CC chemokine receptor 5: the interface of host immunity and cancer

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