cannabinoid receptor

(redirected from CB1 receptor)

cannabinoid receptor

THC receptor, see there.
References in periodicals archive ?
THC is close to a perfect fit for the CB1 receptor.
Indeed, inhibition of peripheral CB1 receptor expression suppressed the analgesic effects of administered cannabinoids in a neuropathic pain model, demonstrating the importance of peripheral CB1 function in cannabinoid-mediated analgesia (26).
Mackie K, Mechanisms of CB1 receptor signaling: endocannabinoid modulation of synaptic strength, International Journal of Obesity (2006) 30, S19-S23.
To date, Larrinaga et al demonstrated that renal tumour tissues expressed mRNA of CB1 receptor in the tubular system of adult kidneys.
According to Krystal, the findings raise the possibility that normalizing cannabinoid CB1 receptor activity might play a role in reducing cannabis use and problems with impulse control in users.
Since marijuana contains compounds that could be dangerous, analyzing how the CB1 receptor works under the influence of cannabis could lead to more knowledge on how synthetic compounds affect the body.
It is 20,000 times more selective for the CB2 receptor than for the CB1 receptor and thereby able to achieve pain relief without the euphoric and other side effects seen with less selective agonists.
Rimonabant, a cannabinoid CB1 receptor antagonist/inverse agonist developed in the mid-1990s, suppresses appetite and weight gain in experimental animals.
33) THCV is a CB1 receptor antagonist and a partial agonist for CB2 receptors.
The fact is that not a lot of other substances hit that CB1 receptor.
According to researchers at INSERM, the CB1 receptor in particular nerve cells within the olfactory system plays a central role in stimulating feeding.
It is thought that the antiemetic and appetite-stimulating effects of Cannabis are mediated by CB1 receptor activation in the hypothalamus.