CAV2

CAV2

A gene on chromosome 7q31.1 that encodes caveolin 2, the main scaffolding protein of the inner surface of caveolae (small invaginations of plasma membranes). Caveolin 2 is involved in essential cellular functions, including signal transduction, lipid metabolism, control of cell growth and apoptosis; it may function as a tumour suppressor.
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The HumanDrive consortium has recently won a grant award from Innovate UK under the CAV2 programme.
Otros genes como CAV1, CAV2 y EHD2 codifican componentes de caveolae que se especializan en las estructuras de membrana plasmatica abundantes en las celulas endoteliales necesarias para la angiogenesis (15).