CASP5

CASP5

A gene on chromosome 11q22.2-q22.3 that encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family which, once activated by proteolytic processing, plays a central role in the execution phase of cell apoptosis; overexpression of activated CASP5 induces apoptosis in fibroblasts. CASP5 is an initiator type caspase, which is activated by, and interacts, with upstream adaptor molecules through CARD and DED protein–protein interaction domains; CASP5 expression is regulated by IFN-gamma and lipopolysaccharides.
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Transforming Growth Factor, Beta Receptor II (TGFRII) [92], Bax [93] and CASP5 (caspase 5) [94].
TABLA III PATRON DE LATENCIA DEL VIRUS EPSTEIN BARR Y NEOPLASIAS ASOCIADAS Latencia Genes virales Neoplasias asociadas expresados I EBNA-1 Linfoma de Burkit EBERs BARF II EBNA-1 Linfoma de Hodgkin EBERs Cancer nasofaringeo LMP-1 Linfoma periferico LMP-2 T/NK BARF III Todos EBNAs Linfomas asociados a EBERs SIDA LMP-1 Desordenes LMP-2 linfoproliferativos BARF Postransplantes TABLA IV GENES CANDIDATOS Y LINFOMAS FAMILIARES Via Genes Ciclo celular/ AICDA, BAX, BCL2,BCL2A1,BCL2L1,BCL2L2, BCL2L10, Apoptosis BCL2L11(BIM), BCL6, BCL7A, BCL7C, BCL10, CASP1, CASP14, CASP4, CASP5, CASP6, CASP7, CASP8AP2, CASP9, CCND1, LMO2, MYC, PIM1, RIPK1, RIPK2, TP53, TP53I.
0: X3M a Computer Program to Extract 3D Models Abstract at the CASP5 conferenceA102, 2002.