CARD10

(redirected from CARMA3)

CARD10

A gene on chromosome 22q13.1 that encodes a protein which activates NF-kappa-B by binding to BCL10 and IKK. It is highly expressed in adult heart, kidney and liver.
References in periodicals archive ?
Recognition of the participation of the CARMA-Bcl10-Malt1 (CBM) signalosome in vital processes in cells continues to emerge, including distinct roles of CARMA1 in immune cells and CARMA3 in epithelial/endothelial cells.
The assembly of the lipid raft-associated CARMA-Bcl10-MALT1 (CBM) signalosome involves CARMA1 in the immune cells and CARMA3 in nonimmune cells [23, 48, 49].