In contrast to the differences we found among CAMRSA
isolates from adults and children, however, the hospital-associated MRSA isolates (>72 hours after admission) had similar rates of antimicrobial drug resistance (Table 3).
have been described as strains harboring the SCCmec type IV, type V, or type VII [8,9] and remained susceptible to the majority of antimicrobial agents other than beta-lactams.
Health care-associated or hospital-acquired MRSA differs from CAMRSA
in terms of epidemiology, phenotype, and genotype (Raygada & Levine, 2009).
has been associated with soft-tissue infections and necrotizing pneumonia, (4) as well as less multidrug resistance than HA-MRSA (2) but higher growth rates,s The Centers for Disease Control and Prevention (CDC) requires all of the following to establish a diagnosis of CA-MRSA (6):
Outpatient treatment for suspected CAMRSA
may include oral trimethoprim-sulfamethoxazole or clindamycin.
The biggest changes in CAMRSA
trends, however, have occurred in children and in skin and soft tissue infections, Dr.
Although invasive CA-MRSA infections are increasingly a concern, skin and soft tissue infections continue to make up the majority of CAMRSA
With the discovery of these genotypic differences we now have a good understanding of how CAMRSA
strains arose independently and abruptly in the community.
carriage predisposes to skin and soft tissue infections (1).
In parts of the United States, CAMRSA
infections currently exceed those caused by their methicillin-susceptible counterparts.