CALGB

Also found in: Acronyms.

CALGB

Cancer and Leukemia Group B. A national (US) clinical research group sponsored by the NCI, with its central office headquartered at the University of Chicago and its statistical centre located at Duke University.

References in periodicals archive ?

Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal stromal tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group.

Predictors of response to targeted therapies for gastrointestinal stromal tumors

The CALGB 8541/150013 substudy [7] investigators did not find evidence for TOP2A as a predictor for anthracycline sensitivity.

Chemosensitivity (and resistance) in breast cancer

Phase III study of irinotecan/5FU/LV (FOLFIRI) or oxaliplatin/5FU/LV (FOLFOX)[+ or -]cetuximab for patients (pts) with untreated metastatic adenocarcinoma of the colon or rectum (MCRC): CALGB 80203 preliminary results.

Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: recommendations from an expert panel

Just how far chemotherapy has come in the past 20 years was best illustrated by a comparison of outcomes between ER-negative participants in CALGB 8541 who were on the standard adjuvant chemotherapy regimen of 20 years ago--low-dose cyclophosphamide, doxorubicin, and fluorouracil--and patients in CALGB 9741 on a much more contemporary regimen of concurrent high-dose doxorubicin and cyclophosphamide followed by paclitaxel with dosing every 2 weeks.

Refined chemo benefits ER-negative patients

The CALGB study (10) showed that for patients with t(8; 21), race was an important prognostic factor.

Core-binding factor acute myeloid leukemia

In CALGB 9082, 785 patients were equally randomized per protocol to consolidation with high- or intermediate-dose cyclophosphamide, cisplatinum, and carmustine (71).

Bone marrow and peripheral blood hematopoietic stem cell transplantation: focus on autografting

He noted a study that evaluated ten-year consecutive trials of young adults (ages 16-21 years) who were participating in either Children's Cancer Group (CCG) or adult CALGB trials.

NCCN Expert Discusses Extending Life-Saving Pediatric Treatments to Adults with Acute Lymphoblastic Leukemia

More recently the CALGB 9781 trial, which was closed early due to poor accrual, reported a long-term survival advantage with the use of chemoradiotherapy followed by surgery in patients with mainly adenocarcinoma of the oesophagus based on the analysis of its 56 enrolled patients [16].

Perioperative management of gastro-oesophageal cancer

Kaufman concluded in his presentation of the CALGB data.

Trastuzumab may benefit HER2-negative patients

Vidaza use in this study was associated with responses similar to those reported in the pivotal CALGB study as published in the Journal of Clinical Oncology in May 2002.

New Data Validate Vidaza(R) Response Rates in MDS and Report Results in AML

Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803.

Annual meeting of the American Society of Clinical Oncology (ASCO), 2008

ORLANDO -- Hopes that the addition of bevacizumab to gemcitabine would improve survival in patients with advanced pancreatic cancer have been dashed by the disappointing results of CALGB 80303, a phase III randomized trial presented at a symposium on gastrointestinal cancers sponsored by the American Society of Clinical Oncology.