Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: A phase 3 trial (CALGB
Impact of Physical Activity on Cancer Recurrence and Survival in Patients with Stage III Colon Cancer: Findings from CALGB
Detection of minimal residual disease following induction immunochemotherapy predicts progression free survival in mantle cell lymphoma: final results of CALGB
Sugar-sweetened beverage intake and cancer recurrence and survival in CALGB
The Breakthrough designation is primarily based upon the positive results from the Phase HI RATIFY (CALGB
10603) clinical trial.
Overall, 22% of the women were deemed by investigators to be eligible for no radiotherapy because they fit the criteria laid out in the CALGB
(Cancer and Leukemia Group B) 9493 study: age 70 years or older, with T1N0, estrogen receptor-positive disease.
Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB
Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB
(2006) (16) found in an analysis of the Intergroup CALGB
study, that physically active patients with bowel cancer had 35% reduction in relapse rate in after chemotherapy.
Phase II trial of galiximab plus rituximab (CALGB
trial) in untreated follicular lymphoma showed that the ORR was 72.1% including a 47.6% CR rate .
Socinski et al., "Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB
30406 trial," Journal of Clinical Oncology, vol.
More recently, the predictive power of hypertension was evaluated in a retrospective analysis of the phase III CALGB
90206 study, which demonstrated that patients on bevacizumab plus interferon who developed grade [greater than or equal to] 2 hypertension had significantly greater progression-free survival and overall survival times than patients who did not develop hypertension .