CA2(redirected from CAII)
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CA2A gene on chromosome 8q22 that encodes an isoenzyme of carbonic anhydrase, a zinc metalloenzyme that catalyses the reversible hydration of carbon dioxide. Carbonic anhydrase 2 is essential for bone resorption and osteoclast differentiation.
CA2 mutations are associated with osteopetrosis and renal tubular acidosis.