CACNB3

CACNB3

A gene on chromosome 12q13 that encodes a beta subunit of a voltage-dependent calcium channel, which plays a regulatory role in calcium channel function by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G
protein inhibition and controlling alpha-1 subunit membrane targeting.
References in periodicals archive ?
In the MAPK pathway, there were 14 differentially expressed genes (P < 0.05): DUSP1, GNA12, RAC1, MRAS, ELK1, ATF4, MAPK3, CDC25B, STMN1, MAX, TGFBR2, MAPK11, CACNB3, FGF8, and RASA2 (Table 5).
In this study 14 MAPK signaling genes were differentially expressed, including GNA12, DUSP1, MAPK11, RAC1, MRAS, ELK1, ATF4, MAPK3, CDC25B, STMN1, MAX, TGFBR2, CACNB3, FGF8, and RASA2 (P < 0.01).
Group KEGG pathway ID and name Count of Percent of compared genes count of genes Normal Hsa04010: MAPK signaling 2 0.30% environment pathway Hsa04620: toll-like receptor 1 0.15% signaling pathway Inflammatory Hsa04010: MAPK signaling 14 0.79% environment pathway Group Gene name P value compared Normal CACNA2D3, PPM1B 0.12000 environment TLR6 0.20000 Inflammatory GNA12, DUSP1, MAPK11, RAC1, environment MRAS, ELK1, ATF4, MAPK3, 0.00000 CDC25B, STMN1, MAX, TGFBR2, CACNB3, FGF8, and RASA2 TABLE 5: Key gene list of signaling pathways related to AS.