CACNA1C

(redirected from CACN2)

CACNA1C

A gene on chromosome 12p13.3 that encodes the alpha-1C subunit of a voltage-dependent N-type calcium channel, which mediates the entry of calcium ions into excitable cells. These channels are also involved in various calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and apoptosis. CACNA1C is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons.

Molecular pathology
Defects of CACNA1C cause Timothy syndrome and Brugada syndrome type 3.
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References in periodicals archive ?
(A) v = 55.905 - 0.4163x, [r.sup.2] = 0.877** garlic extract (mL [L.sup.-1]) 0 56a 14 53ab 28 37cd 42 43bc 56 53cde 70 26de CaCN2 21e H2CN2 23e (B) garlic extract (mL [L.sup.-1]) y = 40.333 - 0.1, [r.sup.2] = 0.8833 ** 0 40a 14 30a 28 38a 42 37a 56 33ab 70 34a CaCN2 23c H2CN2 28bc Note: Table made from Bar graph.
Na busca por novas alternativas para a quebra de dormencia de plantas frutiferas de clima temperado, Kubota & Miyamuki (1992) verificaram que a aplicacao de pasta de alho na regiao do corte de poda de ramos de videiras 'Moscatel de Alexandria' estimulou a brotacao de gemas de forma mais efetiva que a aplicacao de solucao a 20% de calciocianamida (CaCN2), produto tradicionalmente utilizado na viticultura japonesa para esta finalidade.