CA9


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CA9

A gene on chromosome 9p12 that encodes a carbonic anhydrase, a zinc metalloenzyme that catalyses the reversible hydration of carbon dioxide. Carbonic anhydrases participate various biological processes, including respiration, calcification, maintaining acid-base balance, bone resorption and producing aqueous humour, cerebrospinal fluid, saliva and gastric acid. CA9 is a transmembrane protein and the only known tumour-associated carbonic anhydrase isoenzyme, and may be involved in cell proliferation and transformation.
 
Molecular pathology
CA9 is expressed in all clear-cell type renal cell carcinomas, but is not expressed in normal kidney or most other normal organs.
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We found that the CA9 mRNA expression of BCSCs was gradually enhanced after 6-h alkalinization compared to that of non-alkalinized BCSCs (Figure 1B).
The immunoreactivity levels of CA9 and H1F-l[alpha] were classified into four groups: 0%, 1-25%, 26-50%, >50% for CA9; and s1-10%, 11-50%.
Contract grant sponsor: National Research Council of Science and Technology of Mexico (CONACYT); contract grant numbers: 39638-Y, U40177-Y; Contract grant sponsors: Fund for Research Support (FAI) of UASLP, Concurrent Fund (FRC) of UASLP, Academic Group CA9 of FCQ/UASLP.
Co., 543 F.2d 676 (CA9 1976) (damages available against railroad that failed to acquire lawful easement or right of way over Indian reservation); Edwardsen v.
The calculative scale (CALC) was constructed using ten items: Individual performance appraisals at the managerial level (item ca1), at the professional/technical (nonmanagerial)level (item ca2), at the clerical level (item ca3), and at the manual level of employment (item ca4); individual reward systems (merit pay/performance-related pay) at the managerial level (item ca5), at the professional/technical (nonmanagerial) level (item ca6), at the clerical level (item ca7), and at the manual level (item ca8); and formal evaluation of the effectiveness of personnel training immediately after the training has taken place (item ca9) and evaluation some months after training (item ca10).
Michaelian, 86-2 USTC 9798 (CA9, 10-3186); 58 AFTR 2d 86-6105; 803 F2d 1042 (9th Cir., 1986)
Treatment with HABE for 24 h inhibited the viabilities of Ca9-22 gingival and HSC-3 tongue SCC cells by 35% and 26%, respectively, at 50 [micro]g/ml and 58% and 51%, respectively, at 100 [micro]g/ml ([IC.sub.50] = 83 [micro]M for Ca9.22 and 98 [micro]M for HSC-3).
Together with the respiratory syncytial virus, strain Long (RSV), parainfluenza type 3 virus (Para 3), coxsackievirus subtype A9 (CA9), and adenovirus C subtype 5 (Adeno 5) all virus strains were obtained from the former Department of Medical Virology and Epidemiology of Virus Diseases of the Hygiene Institute of the University of Tubingen, Germany.