CA3


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CA3

A gene on chromosome 8q21.2 that encodes a carbonic anhydrase, a zinc metalloenzyme that catalyses the reversible hydration of carbon dioxide. Carbonic anhydrases participate various biological processes, including respiration, calcification, maintaining acid-base balance, bone resorption and producing aqueous humour, cerebrospinal fluid, saliva and gastric acid. Carbonic anhydrase 3 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and other) capillaries and proximal renal tubules; it is thought to have a role in hereditary defects in bicarbonate transport.
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References in periodicals archive ?
As seen from the spectra, the intensity of the bands at 3,200-3,500 [cm.sup.-1] and 1,567 [cm.sup.-1] relatively increases with increasing the grafting percent from CAI to CA3. This is probably due to the increases of -NH groups, quinoid, and benzenoid units in the Ch-g-PANI copolymers.
Information processed by the dentate gyrus gets passed along to the CA3, and then on to CA1.
In adults, mossy fibers normally project to proximal apical dendrites of pyramidal cells in the stratum lucidum (SL) of the CA3 (Figure 1(a)), whereas, during postnatal development, mossy fibers from the immature granule cells extend to both the SL and stratum oriens (SO), forming both suprapyramidal bundles (SPB) and infrapyramidal bundles (IPB), respectively (Figure 1(b)).
Every fifth section (1-in-5 series) containing the dorsal hippocampal CA3 subregion was collected (in PBS 0.1 M).
PND 40 rats supplemented prenatally with either choline or DHA alone shows significantly (* p < 0.05) increased number of neural cells in the CA3 region of hippocampus when compared to the same in age matched normal control and saline control group of rats.
These layers sent outputs to dorsal and ventral dentate gyrus (DG, 2 layers, dorsal and ventral, size 20 x 40 each), CA3 (2 layers size 16 x 16 each), and CA1 (4 layers size 20 x 20 each, Table 1).
In the control group, pyramidal cells in the CA1, CA3 and CA4 regions were densely arranged, and had longer processes and were deeply stained.
activity was statistically significant between groups in the CA1 area of the ventral hippocampus and CA3 area, showing higher C.O.
In addition, Simvastatin (10, 20, and 40mg/kg) significantly reduced the total number of abnormal pyramidal cells in CA1 and CA3 hippocampal regions compared to the picrotoxin-alone group.
An unexpected and key new observation from this study was a substantial and significant increase in cell count number in the dentate gyrus region and specifically CA3 neuron population.