CA2


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CA2

A gene on chromosome 8q22 that encodes an isoenzyme of carbonic anhydrase, a zinc metalloenzyme that catalyses the reversible hydration of carbon dioxide. Carbonic anhydrase 2 is essential for bone resorption and osteoclast differentiation.

Molecular pathology
CA2 mutations are associated with osteopetrosis and renal tubular acidosis.
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References in periodicals archive ?
Updating hippocampal representations: CA2 joins the circuit.
Decoding neurodevelopment: findings environmental exposures and synaptic plasticity
Furthermore, the Israeli Supreme Court's argument, if taken to its logical conclusion, would purport to apply the law of international armed conflict to almost every civil war and, perhaps, even other forms of internal strife previously considered to be definitively outside the scope of CA2. If capabilities alone are sufficient to constitute an international armed conflict, a multitude of non-state actors, not just terrorists, would potentially qualify for the whole swath of Geneva Conventions protections, rendering the body of international law intended to specifically govern non-international armed conflict virtually meaningless.
Conflict classification and detainee treatment in the war against al Qaeda
For instance, a significant preservation of selective vulnerable hippocampal neuronal population in CA1 and CA2 was found in the treatment group via activation of intracellular signaling pathway involved in the promotion of cell survival by expression of anti-apoptotic molecules such as Bcl-2 and Bcl-XL (Morali et al.).
The Effects of Progesterone on Hypoxic Ischemic Injuries in the Cornu Ammonis (CA) Region of the Hippocampus of Neonatal Rats/Efectos de la Progesterona en Lesiones por Hipoxia Isquemica en la Region Cornu Ammonis (CA) del Hipocampo en Ratas Neonatas
(15) In addition, the calcium-activated protease calpain inactivates certain but not all forms of the NCX of the neuron, contributing to the failure to maintain baseline Ca2 + concentrations.
The aging brain part 2: calcium homeostasis and a theory of brain aging
Inhibitory synaptic coverage of CA2 pyramidal cells exceeded that of CA1 pyramidal cells, which was slightly higher than that of dentate granule cells in the control hippocampus (0.80 [+ or -] 0.41 versus 0.64 [+ or -] 0.47 versus 0.53 [+ or -] 0.64).
Synaptic Reorganization of the Perisomatic Inhibitory Network in Hippocampi of Temporal Lobe Epileptic Patients
Internal stores of calcium release the Ca2 + into the cytosol upon activation by signals received across the cell membrane.
The aging brain
The offshore exploration areas were previously identified as Block L and Block M before it was renamed CA1 and CA2.
Malaysia, Brunei ink 'significant' joint oil exploration deal
At the end of experimental study, the brains of mice were removed, and normal and degenerative pyramidal neurons were counted in the hippocampal CA1, CA2, CA3 regions by light microscopy.
The effect of Simvastatin on Picrotoxin-induced seizure in mice
However, the CA2 region lies off the beaten path scientifically and it's not clear what its functions are, Hepler says.
Losing a gene makes mice smarter

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