CA12

CA12

A gene on chromosome 15q22 that encodes a carbonic anhydrase, a zinc metalloenzyme that catalyses the reversible hydration of carbon dioxide. Carbonic anhydrases participate various biological processes, including respiration, calcification, maintaining acid-base balance, bone resorption and producing aqueous humour, cerebrospinal fluid, saliva and gastric acid. The CA12 product is a type-I membrane protein which is highly expressed in normal tissues, such as kidney, colon and pancreas.

Molecular pathology
CA12 is overexpressed in 10% of clear cell carcinomas of the kidney.
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Centrum Length Height Width Atlas-axis complex 15 19 19.5 c3 6.8 ~ 19 c4 7.3 ~ 18.5 c5 7.5 18 19 c6 7.6 18 20 c7 7.8 18.5 19.5 c8 8.0 18 20.5 c9 8.2 18.5 20.7 c10 8.1 19 21 c11 8.2 18.5 21 c12 8.0 19 ~ p1 8.5 ~ ~ d5 14 ~ ~ d13 13 ~ ~ d14 13 17 18 d15 15 ~ ~ d18 14 ~ ~ d22 13.5 15 13 d23 ~ 14 13 s1 11 ~ 13 s3 10 ~ ~ ca2 11 ~ ~ ca4 10 ~ ~ ca5 9 ~ ~ ca7 ~ 12.5 14 ca8 8 13 13.5 ca9 ~ 13 14 ca10 7.5 ~ ~ ca11 8 ~ ~ ca12 ~ 10.5 12.5 ca13 7 10.5 12 Cervical (c), pectoral (p), dorsal (d), sacral (s), and caudal (ca) centra.
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Tabela 2 Estrutura Fatorial do CAD em Jovens Portugueses [xi] [ji al] [lambda] [epsilon] (construto) (variaveis) (erros) [itens] Condutas CA1 0,56 0,31 Antissociais CA2 0,47 0,22 CA3 0,53 0,28 CA4 0,54 0,29 CA5 0,64 0,41 CA6 0,57 0,33 CA7 0,63 0,39 CA8 0,55 0,30 CA9 0,61 0,37 CA10 0,62 0,38 CA11 0,58 0,34 CA12 0,55 0,30 CA13 0,48 0,23 CA14 0,55 0,30 CA15 0,67 0,45 CA16 0,65 0,43 CA17 0,50 0,25 CA18 0,42 0,18 CA19 0,47 0,22 CA20 0,57 0,33 Condutas CD1 0,37 0,14 Delitivas CD2 0,68 0,46 CD3 0,80 0,64 CD4 0,68 0,46 CD5 0,59 0,34 CD6 0,52 0,27 CD7 0,67 0,44 CD8 0,69 0,48 CD9 0,76 0,58 CD10 0,68 0,46 CD11 0,67 0,46 CD12 0,79 0,63 CD13 0,60 0,36 CD14 0,76 0,58 CD15 0,72 0,52 CD16 0,69 0,47 CD17 0,47 0,16 CD18 0,45 0,15 CD19 0,80 0,64 CD20 0,30 0,09 Notas.
The Bt varieties including Tarzan1, MNH886, VH259, BH178, CIM599, IM602, FH142, IR Niab824, IUB222, Saibaan201, Sitara11M, KZ181, Tarzan2, CA12, FH114, and CIM598 should be sown from March 15 to May 15, it was learnt.
NPPC and carbonic anhydrase 12 (CA12) were validated as Gen-induced genes, and interestingly, Dex antagonized Gen-induction for both genes.
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