CA-125


Also found in: Wikipedia.

CA-125

Abbreviation for cancer antigen 125 and the test for it. See: cancer antigen 125 test.

MUC16

A gene on chromosome 19p13.2 which encodes a protein that provides a protective lubricating barrier against particles and infectious agents at mucosal surfaces. It is more commonly known as CA125, and is a highly characteristic marker of ovarian carcinomas.

CA-125

A cell surface glycoprotein expressed on the cell membrane of normal ovarian tissue, ovarian, cervical, endometrium, GI tract, and breast CAs; rising levels indicate a poor prognosis, but low levels are of little clinical utility; CA-125 may also be ↑ in liver disease, acute pancreatitis, renal failure, occasionally in normal ♀, lymphoma
References in periodicals archive ?
Overall, 58% of evaluable patients treated with the therapeutic dose of VB-111 had a GCIG CA-125 response.
Ca-125 is the most frequently used biomarker for ovarian cancer detection.
Objective: To determine the association of CA-125 levels with the peritoneal dissemination among the patients of colo-rectal carcinoma at a tertiary care surgical oncology unit of Pakistan
Preoperative CA-125 levels were determined in 221 patients, of whom elevated CA-125 levels (>35 U/ml) were found in 160 (72.4%) patients, while the median CA-125 level was 65.9 U/ml (range, 7.3-1227.0 U/ml).
* Screening (such as transvaginal ultrasound and/or a tumor marker, CA-125 blood test) does not reduce the mortality due to ovarian cancer.
Her CA-125 level was 29.62 IU/ml (in normal range).
A blood test can be carried out to identify a blood protein that is elevated in many cases of ovarian cancer, called CA-125.
The screening methods used in the trials included transvaginal ultrasound alone, CA-125 testing alone, and transvaginal ultrasound plus CA-125 testing.
Serum concentration of CA-125 during the first trimester of normal and abnormal pregnancies.
Tenders are invited for BarMT 97 / 18-P - reagents and consumables for the automatic biochemical analyzer BA 400; reagents for enzyme immunoassay (ELISA test system CA-125)