Cramer reported that the top-performing marker was CA 125, followed by human epididymis protein 4 (HE4) and CA 72-4
The objective of this study was to compare ten tumor antigens (carcinoembryonic antigen [CEA], CA 19-9, CA 195, CA 50, CA 72-4, CA 125, CA 15-3, CA 27.29, alpha-fetoprotein [AFP], and Cyfra 21-1) for their diagnostic efficacy in gastric cancer patients.
Keywords: cancer, gastric cancer, stomach cancer, carcinoembryonic antigen, alpha-fetoprotein, CEA, AFP, CA 50, CA 19-9, CA 195, CA 72-4, CA 125, CA 15-3, CA 27.29, Cyfra 21-1, tumor marker.
We have selected a panel of tumour-associated antigens that includes the following markers: carcinoembryonic antigen (CEA), prostate specific antigen (PSA), alpha-fetoprotein (AFP), the carbohydrate antigens CA 19-9, CA 15-3, and CA 72-4, and ferritin.
Measurement of tumour-associated antigens: We divided the serum measurements into two groups, following the methods or assays used: IMX system (Abbott diagnostic division), a commercial microparticle enzymatic immunological assay used for measuring ferritin and PSA; and Enzymum-test (Boehringer Mannheim GmbH diagnostic division), a commercial immunoenzyme assay for CEA, CA 72-4, CA 15-3, AFP, and CA 19-9.
A kit for quantitative determination by the enzymatic colorimetric method of the concentration of total cholesterol in human serum and plasma, a kit for the quantitative determination of alpha-amylase activity in blood serum and human urine using the kinetic method, p "the reagent kit tm-ca 72-is intended for the quantitative determination of ca 72-4
(tag-72) in human serum and plasma, oncological antigen and nonspecific oncomarker used for monitoring in stomach and ovarian cancer", "cancer-embryonic antigen (cea) a set of elisa for the determination of cancer-embryonic antigena (cea)", a set of reagents for qualitative and semi-quantitative determination of antistreptolysin o content in the blood serum by the latex agglutination method
Clinical significance of the tumour markers CA 125 II and CA 72-4
in ovarian carcinoma.
CA 72-4, a human tumor-associated glycoprotein (TAG), is frequently used as a tumor marker for diagnosing and predicting prognosis in gastric and ovarian cancers (1819).
The charts and pathologic findings were reviewed in a blinded fashion, without knowing the preoperative serum YKL-40 and CA 72-4 values.
Reagents for diagnostics of cancer marker ca 72-4
On the other hand some previous reports made this hypothesis controversial with the higher positivity rate of CEA CA 72-4
and CA 19-9 in the diffuse type of gastric cancer.3852 Our results showed that there was no significant difference between serum tumor marker levels of patients with respect to tumor grade or the presence of ringlet cell type of tumor cells.
Tiroid fonksiyon testlerinden tiriiyodoti-ronin (T3): 0.91 pg/ml (1.24-3.71), tiroksin (T4): 11.56 pg/ml (7.77-17.1), tiroid stimulan hormon (TSH): 0.72 uIU/m1 (0.27-3.75) anti TPO (tiroid peroksidaz antikoru): 24 U/ml (0-30), anti tiroglobulin: 0.10 IU/m1 (0-70), alfa fetoprotein: 4,3 ng/ml (0-8), karsino embriyonik antijen (CEA): 1,00 ng/ ml (0-10), kanser antijen (CA) 19-9: 5.43 U/ml (0-31), CA 72-4
: 2.39 (0-3.8), total prostat spesifik antijen (PSA): 0.43 ng/ml (0-4), serbest PSA: 0.25 ng/mI (0-1), kompleks PSA: 0.27 ng/ml (0-3), alfa 1 antitripsin: 138 mg/dI (88-174) idi.