CA 27-29

CA 27-29 (Breast carcinoma-associated antigen)

A tumor marker associated with breast cancer.

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I have long questioned why mammograms are often accepted to be the test of choice to diagnose breast cancer, rather than the much less invasive tumor markers, Cancer Antigen 15-3 (CA 15-3), and/or Cancer Antigen 27-29 (CA 27-29).

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Serum tumor markers such as CA 15-3, carcinoembyonic antigen (CEA), and CA 27-29 are ordered in the clinic mainly for disease surveillance, and not useful for detection of localized cancer.

Breast Cancer Screening. Brooks, M. Methods Mol. Biol. 472: 307-321, 2009

The applications of CA 15-3, CA 19-9, CA 27-29, CEA, the estrogen receptors, and HER2/neu are the focus of our continuing discussion of tumor markers and how assays have been used clinically to aid practicing physicians.

The CA 15-3, CA 27-29, and CEA serum markers, together with HER2/neu, are often used as markers for breast cancer.