SERPING1

(redirected from C1IN)

SERPING1

A gene on chromosome 11q12-q13.1 that encodes a highly glycosylated plasma protein which regulates the complement cascade by inhibiting activated C1r and C1s, thereby preventing complement activation.

Molecular pathology
C1-INH/SERPING1 deficiency is associated with hereditary angioneurotic oedema (HANE).
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References in periodicals archive ?
C4 was evaluated using the Cobas C4-2 kit (Roche, Rotkreuz, Switzerland) by Cobas c 501 nephelometry (C4 reference range: 0.1-0.4 g/L), and the C1 INH antigen level was measured using the N AS C1IN kit (Siemens, Marburg Germany) by BN Prospec nephelometry (C1 INH antigen normal range: 0.21-0.39g/L).
We identified environments with the limiting factors "heat stress and/or drought stress" during the grain-filling period (C1in, C2in, C2nr, D1in, D1nr, M1in, M1nr, R1in, R1nr, R2in, R2nr, T1in, T1nr, T2in, and T2nr).