Chlamydia trachomatis

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Chla·myd·i·a tra·cho·ma·tis

spheric nonmotile bacteria that are obligatory intracellular organisms; they form compact intracytoplasmic microcolonies up to 10 mcm in diameter that (by division) give rise to infectious spherules 0.3 mcm or larger in diameter, accumulate glycogen for a limited period in sufficient quantity to be detected by iodine stain, and are usually susceptible to sulfadiazine, tetracycline, and quinalones; various strains of this species cause trachoma, inclusion and neonatal conjunctivitis, lymphogranuloma venereum, mouse pneumonitis, nonspecific urethritis, epididymitis, cervicitis, salpingitis, proctitis, and pneumonia; chief agent of bacterial sexually transmitted diseases in the U.S.; the type species of the genus Chlamydia.
Farlex Partner Medical Dictionary © Farlex 2012

Chlamydia trachomatis

STD A human pathogen, similar to gonorrhea in transmission and disease; it is found in the cervix and urethra and survives in the throat or rectum Epidemiology It is the most common STD agent in the US–causing ± 4.5 million cases/yr; it is present in 1-3% of all ♂ and 15-40% of ♀ in STD clinics Clinical Inclusion conjunctivitis, lymphogranuloma venereum, urethritis, epididymitis and proctitis in ♂, mucopurulent cervicitis, endometritis, salpingitis–C trachomatis is implicated in 50% of salpingitis and PID, bartholinitis, and acute urethral syndrome in ♀ and conjunctivitis and pneumonia in neonates; infection may be asymptomatic Diagnosis Direct fluorescent antibody staining, solid phase immunoassay, ELISA, cell culture, nucleic acid probe, PCR Complications Fallopian tube destruction, ±infertility, ectopic/tubal pregnancy, preterm delivery, severe PID Management Doxycycline, azithromycin. Cf Mycoplasma pneumoniae.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Chla·myd·i·a tra·cho·ma·tis

(klă-mi'dē-a trak-ō'mă-tis)
Spheric nonmotile organisms that accumulate glycogen and are susceptible to sulfadiazine and tetracycline; various strains of this species cause trachoma, inclusion and neonatal conjunctivitis, lymphogranuloma venereum, nonspecific urethritis, epididymitis, cervicitis, salpingitis, proctitis, and pneumonia; chief agent of bacterial sexually transmitted diseases in the U.S. The type species of the genus Chlamydia.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Chlamydia trachomatis

A species that causes a great variety of diseases, including genital infections in men and women. The diseases caused by C. trachomatis include conjunctivitis, epididymitis, lymphogranuloma venereum, pelvic inflammatory disease, pneumonia, trachoma, tubal scarring, and infertility.

C. trachomatis is a commonly sexually transmitted pathogen (causing more than a million chlamydial infections in the U.S. each year). Men with chlamydial infection experience penile discharge and discomfort while urinating. Women may be asymptomatic or may experience urethral or vaginal discharge, painful or frequent urination, lower abdominal pain, or acute pelvic inflammatory disease, which may result in infertility.

Transmission of the disease can be prevented by avoiding contact with infected people and by using condoms during intimate sex. A pregnant woman with a chlamydial infection can transmit the disease to her newborn during birth. In newborns, ophthalmic antibiotic solution should be instilled in the conjunctival sac of each eye to prevent neonatal conjunctivitis and blindness caused by Chlamydia.

Diagnosis

Several tests are available, including cultures, antigen detection assays, ligase chain reactions, polymerase chain reactions, and enzyme-linked immunoassays.

Treatment

Erythromycin, azithromycin, or tetracycline is effective.

CAUTION!

Tetracyclines are generally not recommended for pregnant women or children under 8 years old.
See also: Chlamydia
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
During the study period, 4,228 MSM were triaged as asymptomatic at MSHC and not offered the study but were tested for rectal C. trachomatis and N.
Rectal and oropharyngeal C. trachomatis infection can be diagnosed by testing at the anatomic site of exposure.
This study therefore evaluates prior exposure to C. trachomatis in patients treated for ectopic pregnancy by determining the presence of immunoglobulin G antibodies in their sera.
B10.MLM cells were cultured and infected with C. trachomatis with or without lycopene addition in six-well plates for a postinfection period of 42 hours and then harvested from the plates with trypsin-versene solution.
mRNA levels for three different developmental genes of C. trachomatis were analyzed in McCoy cells after treatment with RESV by quantitative RT-PCR using a CFX-96 thermocycler (Bio-Rad Laboratories, USA).
Autores afirman que aunque la cervicitis se correlaciona con la infeccion endocervical con C. trachomatis o N.
In a survey of studies published during 19982005, the prevalence of C. trachomatis infection among different countries in Europe was presented.
It is reported that infection by C. trachomatis is frequently associated with cervical dysplasia (8) with increased risk in unhealthy cervix.