Chlamydia trachomatis

(redirected from C. trachomatis)
Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

Chla·myd·i·a tra·cho·ma·tis

spheric nonmotile bacteria that are obligatory intracellular organisms; they form compact intracytoplasmic microcolonies up to 10 mcm in diameter that (by division) give rise to infectious spherules 0.3 mcm or larger in diameter, accumulate glycogen for a limited period in sufficient quantity to be detected by iodine stain, and are usually susceptible to sulfadiazine, tetracycline, and quinalones; various strains of this species cause trachoma, inclusion and neonatal conjunctivitis, lymphogranuloma venereum, mouse pneumonitis, nonspecific urethritis, epididymitis, cervicitis, salpingitis, proctitis, and pneumonia; chief agent of bacterial sexually transmitted diseases in the U.S.; the type species of the genus Chlamydia.

Chlamydia trachomatis

STD A human pathogen, similar to gonorrhea in transmission and disease; it is found in the cervix and urethra and survives in the throat or rectum Epidemiology It is the most common STD agent in the US–causing ± 4.5 million cases/yr; it is present in 1-3% of all ♂ and 15-40% of ♀ in STD clinics Clinical Inclusion conjunctivitis, lymphogranuloma venereum, urethritis, epididymitis and proctitis in ♂, mucopurulent cervicitis, endometritis, salpingitis–C trachomatis is implicated in 50% of salpingitis and PID, bartholinitis, and acute urethral syndrome in ♀ and conjunctivitis and pneumonia in neonates; infection may be asymptomatic Diagnosis Direct fluorescent antibody staining, solid phase immunoassay, ELISA, cell culture, nucleic acid probe, PCR Complications Fallopian tube destruction, ±infertility, ectopic/tubal pregnancy, preterm delivery, severe PID Management Doxycycline, azithromycin. Cf Mycoplasma pneumoniae.

Chla·myd·i·a tra·cho·ma·tis

(klă-mi'dē-a trak-ō'mă-tis)
Spheric nonmotile organisms that accumulate glycogen and are susceptible to sulfadiazine and tetracycline; various strains of this species cause trachoma, inclusion and neonatal conjunctivitis, lymphogranuloma venereum, nonspecific urethritis, epididymitis, cervicitis, salpingitis, proctitis, and pneumonia; chief agent of bacterial sexually transmitted diseases in the U.S. The type species of the genus Chlamydia.

Chlamydia trachomatis

A species that causes a great variety of diseases, including genital infections in men and women. The diseases caused by C. trachomatis include conjunctivitis, epididymitis, lymphogranuloma venereum, pelvic inflammatory disease, pneumonia, trachoma, tubal scarring, and infertility.

C. trachomatis is a commonly sexually transmitted pathogen (causing more than a million chlamydial infections in the U.S. each year). Men with chlamydial infection experience penile discharge and discomfort while urinating. Women may be asymptomatic or may experience urethral or vaginal discharge, painful or frequent urination, lower abdominal pain, or acute pelvic inflammatory disease, which may result in infertility.

Transmission of the disease can be prevented by avoiding contact with infected people and by using condoms during intimate sex. A pregnant woman with a chlamydial infection can transmit the disease to her newborn during birth. In newborns, ophthalmic antibiotic solution should be instilled in the conjunctival sac of each eye to prevent neonatal conjunctivitis and blindness caused by Chlamydia.

Diagnosis

Several tests are available, including cultures, antigen detection assays, ligase chain reactions, polymerase chain reactions, and enzyme-linked immunoassays.

Treatment

Erythromycin, azithromycin, or tetracycline is effective.

CAUTION!

Tetracyclines are generally not recommended for pregnant women or children under 8 years old.
See also: Chlamydia
References in periodicals archive ?
In conclusion, this report shows the emergence of genital C.
Autores afirman que aunque la cervicitis se correlaciona con la infeccion endocervical con C.
Association of different STIs with cytological diagnosis Total STIs MLM ASCUS LSIL HSIL positive =ASCUS C.
La evaluacion economica compara los costos y la efectividad (en terminos de las caracteristicas operativas) de las pruebas rapidas: Acon[R]Plate, Acon[R]Duo y QuickVue[R] con el abordaje sindromico, para el diagnostico de cervicitis por C.
Tambien es valedero indagar a profundidad en los hombres con problemas de reproduccion que resultan negativos para infeccion por C.
Como parte de una estrategia para el desarrollo de estudios epidemiologicos a gran escala, el objetivo de este trabajo fue estimar la prevalencia de infecciones causadas por Chlamydia trachomatis en una poblacion de mujeres sexualmente activas, sintomaticas y asintomaticas, que asistieron a consulta de ginecologia en clinicas privadas del municipio Maracaibo, aplicando tecnicas de amplificacion de acidos nucleicos especificos de C.
Debido al deficit de sistemas de diagnostico comerciales en Trinidad, la RCP autoctona es una alternativa economica que puede emplearse para detectar la infeccion asintomatica por C.