Corynebacterium diphtheriae

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Cor·y·ne·bac·te·ri·um diph·the·'ri·ae

a bacterial species that causes diphtheria and produces a powerful exotoxin causing degeneration of various tissues, notably myocardium, in humans and experimental animals, and catalyzing the ADP-ribosylation of elongation factor II; virulent strains of this organism are lysogenic; it is commonly found in membranes in the pharynx, larynx, trachea, and nose in cases of diphtheria; it is also found in apparently healthy pharynx and nose in carriers, and occasionally in the conjunctiva and in superficial wounds; it occasionally infects the nasal passages and wounds of horses; it is the type species of the genus Corynebacterium.
Farlex Partner Medical Dictionary © Farlex 2012

Corynebacterium diphtheriae

The causative agent of diphtheria, which produces a potent exotoxin Reservoir Humans Epidemiology Airborne, infected fomites, infected skin; more common in winter, with crowding, hot, dry air Incidence 5/105–US; attack rate in minorities is 5- to 20-fold that of whites Microbiology In culture, C diphtheriae are often arranged in aggregates fancifully likened to Chinese letters
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Cor·y·ne·bac·te·ri·um diph·the·ri·ae

(kŏ-rī'nē-bak-tēr'ē-ŭm dif-thēr'ē-ē)
Typespecies of the genus Corynebacterium, thecause of diphtheria. It induces a severe membranous pharyngitis and produces an exotoxin that damages myocardium and other tissues; may also infect superficial wounds; an asymptomatic carrier state is common.
Synonym(s): Löffler bacillus.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Corynebacterium diphtheriae

The causative agent of diphtheria in humans.
See: diphtheria
See also: Corynebacterium
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The Minnesota Department of Health confirmed C. diphtheriae status by culture after the initial identification at private institutions or providers using matrix-assisted laser desorption/ ionization time-of-flight spectrometry.
The difference between the confirmation criteria in the two hospital groups is lost after week 24, when Hospital B started doing culture for C. diphtheriae.
While she was receiving medical care, infected insect bites on her lower extremities were noted; wound cultures grew a coryneform isolate (identified as C. diphtheriae via MALDI-TOF and confirmed as toxin-producing).
During the 2015 KwaZulu-Natal diphtheria outbreak investigation, we received 21 C. diphtheriae isolates swabbed from the throat or nasopharynx (or groin in 1 case).
Isolation of C. diphtheriae from a clinical specimen was used to confirm the clinical diagnosis (31).
Use of these tools will minimize the risk of importation of C. diphtheriae into disease-free areas.
We also sequenced and analyzed the tox genes of an additional 8 historical C. diphtheriae isolates from our culture collection using methods described (9,12).
Editorial Note: Diphtheria is caused by toxigenic strains of the bacterium C. diphtheriae and less frequently by C.
After years of stagnation, the number of complete C. diphtheriae genomes has finally started to increase: currently 13 complete and 3 draft genomes are available in GenBank (as of April 14, 2014).
A blood culture obtained from the patient on June 1 was sent to a regional reference laboratory, and C. diphtheriae, biotype mitts, was identified.
In 2004, the first case of sepsis caused by nontoxigenic C. diphtheriae was recorded (2).
Editorial Note: Most cases of diphtheria result from infection with toxin-producing strains of C. diphtheriae; however C.