Corynebacterium diphtheriae

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Cor·y·ne·bac·te·ri·um diph·the·'ri·ae

a bacterial species that causes diphtheria and produces a powerful exotoxin causing degeneration of various tissues, notably myocardium, in humans and experimental animals, and catalyzing the ADP-ribosylation of elongation factor II; virulent strains of this organism are lysogenic; it is commonly found in membranes in the pharynx, larynx, trachea, and nose in cases of diphtheria; it is also found in apparently healthy pharynx and nose in carriers, and occasionally in the conjunctiva and in superficial wounds; it occasionally infects the nasal passages and wounds of horses; it is the type species of the genus Corynebacterium.

Corynebacterium diphtheriae

The causative agent of diphtheria, which produces a potent exotoxin Reservoir Humans Epidemiology Airborne, infected fomites, infected skin; more common in winter, with crowding, hot, dry air Incidence 5/105–US; attack rate in minorities is 5- to 20-fold that of whites Microbiology In culture, C diphtheriae are often arranged in aggregates fancifully likened to Chinese letters

Cor·y·ne·bac·te·ri·um diph·the·ri·ae

(kŏ-rī'nē-bak-tēr'ē-ŭm dif-thēr'ē-ē)
Typespecies of the genus Corynebacterium, thecause of diphtheria. It induces a severe membranous pharyngitis and produces an exotoxin that damages myocardium and other tissues; may also infect superficial wounds; an asymptomatic carrier state is common.
Synonym(s): Löffler bacillus.

Corynebacterium diphtheriae

The causative agent of diphtheria in humans.
See: diphtheria
See also: Corynebacterium
References in periodicals archive ?
During the 2015 KwaZulu-Natal diphtheria outbreak investigation, we received 21 C.
Toxigenicity testing is considered an important criterion for notifying C.
Diphtheria-infected travelers returning to the United States with incubating or untreated disease can transmit C.
Of the 14 household contacts from whom cultures were obtained, C.
A study in Poland showed a discriminatory capacity of some of the VNTR loci in C.
Taking these data and the literature review into consideration, C.
During 2000-2009, a total of 32 deaths caused by diphtheria were reported in Latvia, and 13 deaths (10 caused by C.
Cultures of oropharyngeal swab samples obtained from each person were negative, including cystine tellurite blood agar, which is selective for C.
To the Editor: Toxigenic Corynebacterium ulcerans may cause a zoonotic infection similar to diphtheria caused by C.
Case-patients undergo a smear examination of the characteristic patch of thick gray membrane and samples are cultured for C.
As in the United Kingdom, all cases of diphtheria reported since 1997 were caused by C.
The 12- year-old was initially treated as a contact with 7 days of erythromycin; this treatment was extended to 14 days when the laboratory confirmed C.