CLEC4D

(redirected from C-type lectin receptor)

CLEC4D

A gene on chromosome 12p13.31 that encodes a C-type lectin domain protein which acts as an endocytic receptor. It is thought to be involved in antigen uptake at the site of infection, either clearing the antigen, or processing it and presenting it to T cells.
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My approach to increase our understanding of fungal immune recognition is to (1) Characterize C-type lectin receptor complexes that drive innate recognition of C.
DNGR-1 (also known as CLEC9A) is a DC-restricted C-type lectin receptor (CLR) that recognizes the actin cytoskeleton exposed on necrotic cells.

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