CLEC4C(redirected from C-type lectin domain family 4 member C)
CLEC4CA gene on chromosome 12p13.2-p12.3 that encodes a C-type lectin domain protein involved in antigen capture, targeting ligands to peptide-loading compartments for presentation to T-cells. CLEC4C may downregulate IFN-alpha/beta expression in plasmacytoid dendritic cells; it may also act as a signalling receptor, activating protein-tyrosine kinases and mobilising intracellular calcium.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.