Our results also indicated that c-kit
expression was higher in the white cashmere goat than in the black goat, and this significant difference was detected by q-PCR and western blotting.
Background and Objective: To evaluate usefulness of immunohistochemical marker C-kit
(CD117) in differentiating Adenoid cystic carcinoma (AdCC) from Polymorphous low-grade adenocarcinoma (PLGA) in patients of salivary gland carcinomas.
The deposition of iron into LSK cells (Lin-Sca-1 + c-kit
+) was assessed using hematoxylin and eosin (HE) staining and Perls' iron staining.
Myelosuppressive effects are also noted, such as anemia, thrombocytopenia, and leukopenia, and are presumably mediated through c-kit
mutations should be included in risk stratification.
Chromophobe renal cell carcinomas are typically c-kit
(CD117)-positive and variably positive for cytokeratin 7 (CK7), whereas oncocytomas are typically positive for c-kit
(CD117) and show very focal scattered positivity for CK7.
Recognition of transmembrane tyrosine kinase receptor, c-kit
through conventional immunohistochemistry has been evolved as valuable adjunct to routine light microscopy for highlighting the ICCs distribution.
Aims: To assess the rate of C-KIT
positivity and its effect on survival of surgically treated sinonasal malignant melanoma patients with other histopathological biomarkers and clinical features.
Furthermore, imatinib, as a tyrosine kinase inhibitor for c-KIT
or PDGFRA, is extensively used in treating GST.
Gain-of-function mutations of c-kit
in human gastrointestinal stromal tumors.
Recently, Oct-4 and c-kit
were reported to be experessed in buffalo testis and spermatogonail stem cells (Xie et al.
A set of mutations termed "internal tandem duplications" (ITD) affecting the exon 11 of the c-kit
gene has been associated with the development of some mast cell tumors in dogs (LONDON et al.