In human injury response, c-Fos
is paired with the gene c-Jun.
In contrast to c-Fos
, Egr-1, and NPY-R, an ortholog for the immediate-early gene Arc has not been detected in zebrafish.
immunohistochemistry has been used to study neural activation patterns in a variety of brain regions following brief periods of enhanced sensory stimulation (e.g., [15-19]).
protein is composed of 380 amino acids with a molecular weight of 55 kD .
We performed quantitative RT-PCR and Western blotting to assess the expression of ATF2, IL-1[beta], IL-6, TNF, c-Fos
, and c-Jun at the protein level.
(21.) Janknecht R, Cahill MA, Nordheim A (1995) Signal integration at the c-fos
Elevated expression of c-fos
in central nervous system correlates with visceral hypersensitivity in irritable bowel syndrome (IBS): a new target for IBS treatment.
serves as a marker of active neurons , and the expression of glial fibrillary acidic protein (GFAP) is a sign of active glial cells .
To investigate the effects of SMS on the osteoclastogenesis of HPDLSCs and PPDLSCs, the osteoclastogenesis-related genes RANKL and C-fos
were examined by real-time RT-PCR.
For the estimation of c-Fos
, NF-[kappa]Bp65, and histone, 12 [micro]g of protein from each nuclear fraction was electrophoresed through 10% sodium dodecylsulfate polyacrylamide gel (SDS-PAGE).
The role of JNK and p38 MAPK activities in UVA-induced signaling pathways leading to AP-1 activation and c-Fos
In addition, according to the researchers, "AP-1 consists of both Fos and Jun genes' family members, which include c-Fos
and c-Jun." The c-Fos
protein has been previously found to briefly up-regulated in HCC's early stages and then quickly declines in the later stages of tumor progression - a process "for priming hepatocytes [predominant main cells of the liver] for migration and tissue invasion," Youssef and her team explained.