CCL7(redirected from C-C motif chemokine 7)
CCL7A gene on chromosome 17q11.2-q12 that encodes monocyte chemotactic protein 3 (MCP-3), a secreted chemokine that attracts macrophages during inflammation and metastasis. MCP-3/CCL7 is a member of the C-C subfamily of chemokines, which have two adjacent cysteine residues, and is a ligand for CCR1, CCR2 and CCR3. It is an in vivo substrate of matrix metalloproteinase 2, an enzyme that degrades the extracellular matrix.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.