CCR4

(redirected from C-C chemokine receptor type 4)

CCR4

A gene on chromosome 3p24 that encodes a G protein-coupled receptor for C-C-type chemokines (MIP-1, RANTES, TARC and MCP-1). CCR4 is a high-affinity receptor for the C-C-type chemokines CCL17/TARC and CCL22/MDC; its activity is mediated by Gi proteins, which activate phosphatidylinositol-calcium second messengers.
References in periodicals archive ?
Global Markets Direct's, 'C-C Chemokine Receptor Type 4 (C-C CKR-4 or K5-5 or CD194 or CCR4) - Pipeline Review, H1 2016', provides in depth analysis on C-C Chemokine Receptor Type 4 (C-C CKR-4 or K5-5 or CD194 or CCR4) targeted pipeline therapeutics.
The report provides comprehensive information on the C-C Chemokine Receptor Type 4 (C-C CKR-4 or K5-5 or CD194 or CCR4), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
The report provides a snapshot of the global therapeutic landscape for C-C Chemokine Receptor Type 4 (C-C CKR-4 or K5-5 or CD194 or CCR4)